Zinc Citrate is a "Nutrient Dense" Krebs Cycle Chelate which is a bio-available delivery form of Zinc - a mineral which plays a very central role in the immune system.

Zinc affects virtually all aspects of the immune system, from non specific barrier functions of the passive immune system (skin, mucous membranes etc.,) to the specific lymphocytic functions of the active immune system. Zinc functions as an antioxidant and a membrane stabilizer. Zinc citrate supplements this vital mineral Zinc, which is involved in all the four immune defense components. Nonspecific passive, non-specific active cell-mediated and antibody (humoral) mediated. Zinc also plays important roles in growth which extends outside of the pituitary level.

Zinc Citrate represents a totally reacted and nutritionally functional chelate of Zinc and the naturally occurring Citrate in the human body.

Zinc Citrate has the added benefits of better absorption, greater tolerance and enhanced physiological benefits.

Structure

Requirements

The Food and Nutrition Board of the Nutrition Board of the National Academy of Sciences has recommended the following Recommended Dietary Allowances (RDA) for zinc.

Age (years) RDA (milligrams/day)
0 – 1 05
1 – 10 10
Males 11 – 51+ 15
Females 11 – 51+ 12
Pregnant 15
Lactating
First 6 months 19
Second 6 months 16

Importance of Zinc – a multifaceted micromineral

Zinc is a component in over 200 enzymes and is involved in more enzymatic reactions than any other mineral. It is essential to many harmones such as thymic harmones, insulin growth and sex harmones.

Zinc is a micro-mineral that plays important roles in immunity, wound healing, normal growth and development, reproduction, and various metabolic process. Recent research indicates that it may help fight the common cold and other infection; it may also be useful in treating fibromyalgia, osteoporosis, and rheumatoid arthritis.

Zinc is essential in human and animal nutrition with a wide range of biological roles. Zinc plays catalytic, structural and regulatory roles in more than 200 zinc metalloenzymes that have been identified in biological systems. These enzymes are involved in nucleic acid and protein metabolism and the production of energy among other things. Zinc plays structural roles in so called Zinc fingers. Zinc fingers are exploited by transcription factors for interacting with DNA and regulating the activity of genes. Another structural role of zinc is in the maintenance of the integrity of biological membranes resulting in their protection against oxidative injury, among other things.

Role of Zinc in Human Nutrition

Zinc is involved in well over one hundred metabolic process and body functions,

Normal growth and development

Maintaining healthy skin and bones

Essential in various metabolic processes

Healing and immune functions

Physiologically, zinc is vital for growth and developments, sexual maturation and reproduction, dark vision adaptation, olfactory and gustatory activity, insulin storage and release and for a variety of host immune defenses, among other things. Zinc deficiency can result in growth retardation, immune dysfunction, increased incidence of infections, hyypogonadism, oligospermia, anorexia, diarrhea, weight loss, delayed wound healing, neural tube defects of the fetus, increased risk for abortion, alopecia, mental lethargy and skin changes.

Zinc may have immunomodulatory activity. It may also have antioxidant activity. Zinc has putative antiviral, fertility- enhancing and retinoprotective activities.

Effects of Zinc Deficiency

Even borderline zinc deficiency or disturbances in zinc metabolism can have profound adverse health effects. Those at greatest risk of such deficiencies and disturbances include infants, children, the elderly and pregnant women. Due to conditions that can limit the bioavailability of zinc, even when there is adequate zinc intake, zinc deficiency may affect still larger population.

Among diseases and conditions associated with zinc deficiency are alcoholism, malabsorption syndromes, acrodermatitis enteropathica, anorexia nervosa, thermal burns and total parenteral nutrition without zinc supplementation.

Zinc Supplementation as Zinc Citrate

Supplemental zinc may be helpful in some of the foregoing, in some conditions of immune impairment, in some complications of pregnancy, in the prevention of some cases of fetal neural tube defects, diarrhea, oligospermia, delayed wound healing and some cognitive disorders. It may also help against some inflammatory disorders.

Zinc is essential for proper formation and maturation of spermatozoa. There is some evidence that zinc can promote and accelerate wound healing in some circumstances. Zinc is also very important to the newborn when breast milk may be its only source of Zinc.

Zinc Citrate represents a totally reacted and nutritionally functional Chelate of Zinc and the naturally occurring citrate in the human body.

Zinc citrate caters to the need of "optimal mineral nutrition" with respect to zinc by delivering it in a more bio-available, energy rich, tolerant and safe form.

 


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